Genetic Analysis Workshop 18: Methods and Strategies for Analyzing Human Sequence and Phenotype Data in Members of Extended Pedigrees

Authors

Heike BickebollerFollow
Julia N. BaileyFollow
Joseph Beyene
Rita M. CantorFollow
Heather J. Cordell
Robert C. CulverhouseFollow
Corinne D. EngelmanFollow
David W. Fardo
Saurabh GhoshFollow
Inke R. KonigFollow
Justo Lorenzo Bermejo
Phillip E. Melton
Stephanie A. Santorico
Glen A. Satten
Lei Sun
Nathan L. Tintle, Dordt CollegeFollow
Andreas ZieglerFollow
Jean W. MacCluerFollow
Laura AlmasyFollow

Document Type

Conference Proceeding

Publication Date

6-17-2014

Department

Mathematics, Statistics, and Computer Science

Keywords

genetic analysis, genotype-phenotype

Abstract

Genetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.

Comments

From Genetic Analysis Workshop 18, Stevenson, WA, USA. 13-17 October 2012

Source Publication Title

BMC Proceedings

Volume

8

Issue

Supplement 1

First Page

S1

DOI

10.1186/1753-6561-8-S1-S1

Recommended Citation

Bickeböller et al.: Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees. BMC Proceedings 2014 8(Suppl 1):S1.